The aim of the course is an in-depth understanding of:
a) the structure and function of various ribonucleic acids (RNA) with emphasis on the RNAs involved in translation (i.e. mRNA, tRNA, rRNA).
b) the molecular events taking place during the prokaryotic and eukaryotic translation.
c) the molecular events taking place during the eukaryotic and prokaryotic replication.
Upon successful completion of the course, students will have acquired knowledge and understanding of:
· The structure, the life cycle and the sub-cellular localization of prokaryotic and eukaryotic mRNA.
· The maturation process and structure of tRNA and its role in translation.
· The structure of prokaryotic and eukaryotic ribosomes and their role in translation.
· The molecular events taking place during the various stages of prokaryotic and eukaryotic translation and the various factors involved in these stages.
· The structure, function and proofreading mechanisms of aminoacyl-tRNA synthetases.
· The characteristic features of the genetic code, the deviations from the standard genetic code and the various recoding phenomena.
· The molecular events taking place during prokaryotic and eukaryotic DNA replication and the various factors involved in these processes.
The mechanisms of DNA replication, including the mechanism of replication of mitochondrial DNA.
| Name | Capacity | |
|---|---|---|
| Palaiologou Katerina | Assistant Professor | apalaiol@mbg.duth.gr |
