ECTS:

4

Course Outline
e-Class

The overall objective of the course is to provide to the students the theoretical background and to familiarize them with the methodologies and applications of Systems Biology.

The objectives of the course are:
·     To understand the complexity that defines the field of Systems Biology.
·     To familiarize with the approaches applied in big scale datasets.
·     To study the basic principles of constructing biological networks.
·     To study the holistic approaches and basic principles of chromatin organization and gene regulation.
·     To understand that in modern biology, holistic approaches are applied in order to decode the complexity of biological systems, which are based on the notion that networks are a sum of their units. Thus, Systems Biology is studying a “forest” and not a single “tree”.

Learning outcomes
Upon the successful completion of the course, the students will be able:
·     To know the basic theories and principles of Systems Biology and their impact on Biosciences.
·     To understand that the combination of the experimental and computational biology can provide the answer on various complex questions.
·     To understand the basic principles of the chromatin organization and compartmentalization (1D -> 4D), their relationship to transcription factories, chromatin re-organization, regulatory elements, transcription factories and their role in various biological processes with emphasis on gene regulation.
·     To familiarize with the basic methodologic approaches of Systems Biology and to appreciate and understand the obtained results.
To identify the various biological networks and to be able to apply the basic principles of constructing biological networks

Name Capacity Email
Kolovos Petros Associate Professor pkolovos@mbg.duth.gr